Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | inhibits the neutral trehalase in presence of 5 mM trehalose | [Humicola] grisea var. thermoidea | |
1,10-phenanthroline | inhibits the acid trehalase, inhibits the neutral trehalase in presence of 5 mM trehalose | Mycothermus thermophilus | |
ATP | - |
[Humicola] grisea var. thermoidea | |
ATP | - |
Mycothermus thermophilus | |
ATP | - |
Thermochaetoides thermophila | |
EDTA | - |
[Humicola] grisea var. thermoidea | |
EDTA | - |
Mycothermus thermophilus | |
EDTA | - |
Thermochaetoides thermophila | |
gentiobiose | slight inhibition of acid trehalase | [Humicola] grisea var. thermoidea | |
gentiobiose | slight inhibition of acid trehalase | Mycothermus thermophilus | |
metal chelators | - |
[Humicola] grisea var. thermoidea | |
metal chelators | - |
Mycothermus thermophilus | |
metal chelators | - |
Thermochaetoides thermophila | |
methyl-alpha-glucoside | slight inhibition of acid trehalase | [Humicola] grisea var. thermoidea | |
methyl-alpha-glucoside | slight inhibition of acid trehalase | Mycothermus thermophilus | |
phloretin | inhibits the acid trehalase, inhibits the neutral trehalase in presence of 20 mM trehalose | [Humicola] grisea var. thermoidea | |
phloretin | inhibits the acid trehalase, inhibits the neutral trehalase in presence of 20 mM trehalose | Mycothermus thermophilus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Km of neutral and acid trehalase at different temperatures and pH values | Mycothermus thermophilus | |
additional information | - |
additional information | Km of neutral and acid trehalase at different temperatures and pH values | [Humicola] grisea var. thermoidea |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | acid trehalase | Thermochaetoides thermophila | - |
- |
extracellular | acid trehalase | Mycothermus thermophilus | - |
- |
extracellular | acid trehalase | [Humicola] grisea var. thermoidea | - |
- |
intracellular | neutral trehalase | Thermochaetoides thermophila | 5622 | - |
intracellular | neutral trehalase | Mycothermus thermophilus | 5622 | - |
intracellular | neutral trehalase | [Humicola] grisea var. thermoidea | 5622 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | activates | Thermochaetoides thermophila | |
Ca2+ | activates | Mycothermus thermophilus | |
Ca2+ | activates, dependent on pH | [Humicola] grisea var. thermoidea | |
gentiobiose | activates the neutral trehalase | Mycothermus thermophilus | |
gentiobiose | activates the neutral trehalase | [Humicola] grisea var. thermoidea | |
Mn2+ | activates | Thermochaetoides thermophila | |
Mn2+ | activates | Mycothermus thermophilus | |
Mn2+ | activates | [Humicola] grisea var. thermoidea | |
phloretin | activates the neutral trehalase in presence of 5 mM trehalose | Mycothermus thermophilus | |
phloretin | activates the neutral trehalase in presence of 5 mM trehalose | [Humicola] grisea var. thermoidea |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha,alpha-trehalose + H2O | Thermochaetoides thermophila | - |
2 D-glucose | - |
? | |
alpha,alpha-trehalose + H2O | Mycothermus thermophilus | - |
2 D-glucose | - |
? | |
alpha,alpha-trehalose + H2O | [Humicola] grisea var. thermoidea | - |
2 D-glucose | - |
? | |
alpha,alpha-trehalose + H2O | Mycothermus thermophilus 77.7.8 | - |
2 D-glucose | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycothermus thermophilus | - |
isolated from indian soil | - |
Mycothermus thermophilus 77.7.8 | - |
isolated from indian soil | - |
Thermochaetoides thermophila | - |
- |
- |
[Humicola] grisea var. thermoidea | - |
isolated from brazilian soil | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | acid trehalase | Thermochaetoides thermophila |
glycoprotein | acid trehalase | Mycothermus thermophilus |
glycoprotein | acid trehalase | [Humicola] grisea var. thermoidea |
Purification (Comment) | Organism |
---|---|
- |
Mycothermus thermophilus |
- |
[Humicola] grisea var. thermoidea |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
activities of neutral and acid trehalase at different pH values and temperatures | Mycothermus thermophilus |
additional information | - |
activities of neutral and acid trehalase at different pH values and temperatures | [Humicola] grisea var. thermoidea |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha,alpha-trehalose + H2O | - |
Thermochaetoides thermophila | 2 D-glucose | - |
? | |
alpha,alpha-trehalose + H2O | - |
Mycothermus thermophilus | 2 D-glucose | - |
? | |
alpha,alpha-trehalose + H2O | - |
[Humicola] grisea var. thermoidea | 2 D-glucose | - |
? | |
alpha,alpha-trehalose + H2O | - |
Mycothermus thermophilus 77.7.8 | 2 D-glucose | - |
? |
Synonyms | Comment | Organism |
---|---|---|
acid trehalase | - |
Thermochaetoides thermophila |
acid trehalase | - |
Mycothermus thermophilus |
acid trehalase | - |
[Humicola] grisea var. thermoidea |
neutral trehalase | - |
Thermochaetoides thermophila |
neutral trehalase | - |
Mycothermus thermophilus |
neutral trehalase | - |
[Humicola] grisea var. thermoidea |
trehalase | - |
Thermochaetoides thermophila |
trehalase | - |
Mycothermus thermophilus |
trehalase | - |
[Humicola] grisea var. thermoidea |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
additional information | - |
the acid trehalase shows a higher temperature optimum than the neutral trehalase | Thermochaetoides thermophila |
60 | - |
the acid trehalase shows a higher temperature optimum than the neutral trehalase | Mycothermus thermophilus |
60 | - |
the acid trehalase shows a higher temperature optimum than the neutral trehalase | [Humicola] grisea var. thermoidea |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | 60 | - |
[Humicola] grisea var. thermoidea |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
additional information | - |
the acid trehalase is more thermostable than the neutral trehalase | Thermochaetoides thermophila |
additional information | - |
the acid trehalase is more thermostable than the neutral trehalase | Mycothermus thermophilus |
additional information | - |
the acid trehalase is more thermostable than the neutral trehalase | [Humicola] grisea var. thermoidea |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
4.5 | - |
acid trehalase | Mycothermus thermophilus |
4.5 | - |
acid trehalase | [Humicola] grisea var. thermoidea |
6.5 | - |
neutral trehalase | Mycothermus thermophilus |
6.5 | - |
neutral trehalase | [Humicola] grisea var. thermoidea |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
4.5 | 7 | - |
Mycothermus thermophilus |
4.5 | 7 | - |
[Humicola] grisea var. thermoidea |