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Literature summary for 3.2.1.23 extracted from

  • Sopelsa, A.M.; Severini, M.H.; da Silva, C.M.; Tobo, P.R.; Giugliani, R.; Coelho, J.C.
    Characterization of beta-galactosidase in leukocytes and fibroblasts of GM1 gangliosidosis heterozygotes compared to normal subjects (2000), Clin. Biochem., 33, 125-129.
    View publication on PubMed
Search for more literature for 3.2.1.23

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.59
-
 4-methylumbelliferyl beta-D-galactoside fibroblast enzyme of GM1 gangliosidosis heterozygotes Homo sapiens
0.65
-
 4-methylumbelliferyl beta-D-galactoside leukocyte enzyme of GM1 gangliosidosis heterozygotes Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast of GM1 gangliosidosis heterozygotes compared to normal subjects Homo sapiens
-
leukocyte of GM1 gangliosidosis heterozygotes compared to normal subjects Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-methylumbelliferyl beta-D-galactoside + H2O
-
 Homo sapiens 4-methylumbelliferone + beta-D-galactose
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
42
-
 80 min,75% loss of leukocte enzyme from GM1 gangliosidosis heterozygotes,70% loss of fibroblast enzyme from GM1 gangliosidosis heterozygotes Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4
-
 leukocyte enzyme of GM1 gangliosidosis heterozygotes Homo sapiens
4.2
-
 enzyme from leukocytes and fibroblasts of normal individuals, and fibroblast enzyme of GM1 gangliosidosis heterozygotes Homo sapiens