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Literature summary for 3.2.1.22 extracted from
- Trihexosylceramide alpha-galactosidase of human leucocytes (1978), Clin. Chim. Acta, 89, 35-45.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no activity in absence of detergent, optimal detergent concentration 2-4 mg/ml | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ceramide lactoside | - |
Homo sapiens |  |
| EDTA | - |
Homo sapiens | |
| galactose | - |
Homo sapiens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.09 | 0.15 | ceramide trihexoside | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leukocyte | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ceramide trihexoside + H2O | - |
Homo sapiens | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 4.4 | - |
- |
Homo sapiens |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 3.5 | 5.5 | pH 3.5 about 60% of maximal activity, pH 5.5 about 10% of maximal activity | Homo sapiens |
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Release 2023.1 (January 2023)
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