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Literature summary for 3.2.1.207 extracted from
- Biogenesis of lysosomal enzymes in the alpha-glucosidase II-deficient modA mutant of Dictyostelium discoideum Retention of alpha-1,3-linked glucose on N-linked oligosaccharides delays intracellular transport but does not alter sorting of alpha-mannosidase or beta-glucosidase (1989), Arch. Biochem. Biophys., 273, 479-490 .
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum | - |
Dictyostelium discoideum | 5783 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Dictyostelium discoideum | Q94502 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ModA | - |
Dictyostelium discoideum |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | lack of ModA activity does not prevent intracellular transport and proteolytic processing of the lysosomal enzymes, alpha-mannosidase and beta-glucosidase, but slows down the rate at which the glucosylated precursors leave the rough endoplasmic reticulum. Enzymes N-acetylglucosaminidase and acid phosphatase are secreted much less efficiently from lysosomal compartments by the mutant strain | Dictyostelium discoideum |
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