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Literature summary for 3.2.1.207 extracted from

  • Kiappes, J.; Hill, M.; Alonzi, D.; Miller, J.; Iwaki, R.; Sayce, A.; Caputo, A.; Kato, A.; Zitzmann, N.
    ToP-DNJ, a selective inhibitor of endoplasmic reticulum alpha-glucosidase II exhibiting antiflaviviral activity (2018), ACS Chem. Biol., 13, 60-65 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.1.207

Inhibitors

Inhibitors Comment Organism Structure
(1S,2R,3R,4R)-4-(hydroxymethyl)-5-[5-([(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-yl]oxy)pentyl]cyclohexane-1,2,3-triol inhibitor affects only myeloid lineage immune cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Huh-7.5 cell
-
 Homo sapiens
-
macrophage
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
ER glucosidase II
-
 Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.009
-
 pH not specified in the publication, temperature not specified in the publication Homo sapiens (1S,2R,3R,4R)-4-(hydroxymethyl)-5-[5-([(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-yl]oxy)pentyl]cyclohexane-1,2,3-triol