Any feedback?
Literature summary for 3.2.1.20 extracted from
- Comparison of maltose and acarbose as inhibitors of maltase-glucoamylase activity in assaying acid alpha-glucosidase activity in dried blood spots for the diagnosis of infantile Pompe disease (2006), Genet. Med., 8, 302-306.
General Stability
| General Stability | Organism |
|---|---|
| neutral alpha-glucosidase is less stable than acid alpha-glucosidase | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| acarbose | - |
Homo sapiens |  |
| maltose | - |
Homo sapiens | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | a severe form of enzyme deficiency causes the infantile Pompe disease | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
patients with infantile Pompe disease | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood | dried blood spot specimen from patients with infantile Pompe disease | Homo sapiens | - |
| fibroblast | - |
Homo sapiens | - |
| skin | fibroblasts | Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-methylumbelliferyl-alpha-D-glucopyranoside + H2O | - |
Homo sapiens | 4-methylumbelliferol + alpha-D-glucose | - |
? | |
| additional information | a severe form of enzyme deficiency causes the infantile Pompe disease | Homo sapiens | ? | - |
? | |
| additional information | development and evaluation of an assay method for enzyme detection in dried blood spot specimen from patients with infantile Pompe disease, overview | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| acid alpha-glucosidase | - |
Homo sapiens |
| maltase-glucoamylase | - |
Homo sapiens |
| neutral alpha-glucosidase | - |
Homo sapiens |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 3.8 | - |
acid alpha-glucosidase assay at | Homo sapiens |
| 7 | - |
neutral alpha-glucosidase assay at | Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
