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Literature summary for 3.2.1.20 extracted from
- Purification and biochemical characterisation of human placental acid alpha-glucosidase (1997), Biochem. Mol. Biol. Int., 42, 1051-1061.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| D-glucono-delta-lactone | - |
Homo sapiens |  |
| methyl-alpha-D-glucopyranoside | no inhibition of maltose hydrolysis, competitive inhibition of glycogen hydrolysis | Homo sapiens | |
| sucrose | no inhibition of maltose hydrolysis, competitive inhibition of glycogen hydrolysis | Homo sapiens | |
| trehalose | no inhibition of maltose hydrolysis, competitive inhibition of glycogen hydrolysis | Homo sapiens | |
| Tris | - |
Homo sapiens | |
| turanose | - |
Homo sapiens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 2 | - |
maltose | - |
Homo sapiens | |
| 2 | - |
maltotriose | - |
Homo sapiens | |
| 2.35 | - |
maltopentaose | - |
Homo sapiens | |
| 3.1 | - |
maltotetraose | - |
Homo sapiens | |
| 11.11 | - |
p-nitrophenyl-alpha-D-glucopyranoside | - |
Homo sapiens | |
| 15.4 | - |
starch | - |
Homo sapiens | |
| 30 | - |
glycogen | - |
Homo sapiens | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| lysosome | - |
Homo sapiens | 5764 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 150000 | - |
non-denaturing PAGE | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | contains 23% carbohydrate by weight | Homo sapiens |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| placenta | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 32 | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glycogen + H2O | - |
Homo sapiens | alpha-D-glucose | - |
? | |
| maltopentaose + H2O | - |
Homo sapiens | alpha-D-glucose + ? | - |
? | |
| maltose + H2O | - |
Homo sapiens | alpha-D-glucose + D-glucose | - |
? | |
| maltotetraose + H2O | - |
Homo sapiens | alpha-D-glucose | - |
? | |
| maltotriose + H2O | - |
Homo sapiens | maltose + D-glucose | - |
? | |
| p-nitrophenyl-alpha-D-glucopyranoside + H2O | - |
Homo sapiens | 4-nitrophenol + D-glucose | - |
? | |
| palatinose + H2O | - |
Homo sapiens | alpha-D-glucose + D-fructose | - |
? | |
| starch + H2O | - |
Homo sapiens | alpha-D-glucose | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | - |
Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 4.5 | - |
hydrolysis of maltose | Homo sapiens |
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