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Literature summary for 3.2.1.20 extracted from
- Characterization of neutral isozymes of human alpha-glucosidase: differences in substrate specificity, molecular weight and electrophoretic mobility (1981), Biochim. Biophys. Acta, 658, 248-261.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Hg2+ | - |
Homo sapiens |  |
| maltose | hydrolysis of 4-methylumbelliferyl-alpha-glucoside | Homo sapiens | |
| Mn2+ | - |
Homo sapiens | |
| turanose | - |
Homo sapiens | |
| Zn2+ | - |
Homo sapiens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Homo sapiens |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 92000 | - |
alpha-glucosidase C, gel filtration | Homo sapiens |
| 150000 | - |
alpha-glucosidase AB, gel filtration | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
alpha-glucosidase AB and alpha-glucosidase C | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-methylumbelliferyl-alpha-glucoside + H2O | - |
Homo sapiens | 4-methylumbelliferone + alpha-D-glucose | - |
? | |
| maltose + H2O | - |
Homo sapiens | alpha-D-glucose + D-glucose | - |
? | |
| additional information | alpha-glucosidase C releases alpha-D-glucose from glycogen as well as from low molecular weight artificial and natural substrates. alpha-glucosidase AB does not utilize alpha-1,4 linked glucose substrates larger than a disaccharide | Homo sapiens | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
4-methylumbelliferyl-alpha-glucoside | Homo sapiens |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5.5 | 8.5 | pH 5.5: about 25% of maximal activity, alpha-glucosidase AB. About 30% of maximal activity, alpha-glucosidase C. pH 8.5: about 45% of maximal activity, alpha-glucosidase AB. About 70% of maximal activity, alpha-glucosidase C | Homo sapiens |
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