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Literature summary for 3.2.1.20 extracted from
- Identity of alpha-glucosidase of human kidney with urine F-1 alpha-glucosidase (1982), J. Biochem., 91, 809-816.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Hg2+ | HgCl2 | Homo sapiens |  |
| Nojirimycin | - |
Homo sapiens | |
| PCMB | - |
Homo sapiens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.15 | - |
maltotriitol | - |
Homo sapiens | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 30000 | - |
gel filtration | Homo sapiens |
| 33000 | - |
1 * 33000, SDS-PAGE | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Homo sapiens | - |
| urine | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 23.5 | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glycogen + H2O | - |
Homo sapiens | alpha-D-glucose | - |
? | |
| maltose + H2O | - |
Homo sapiens | alpha-D-glucose + D-glucose | - |
? | |
| maltotriitol + H2O | - |
Homo sapiens | ? | - |
? | |
| starch + H2O | - |
Homo sapiens | alpha-D-glucose | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 33000, SDS-PAGE | Homo sapiens |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 50 | - |
15 min, stable up to | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 4.6 | - |
- |
Homo sapiens |
| 5.6 | - |
hydrolysis of maltotriitol and potato starch | Homo sapiens |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 4 | 7 | pH 4.0: about 60% of maximal activity with potato starch as substrate, about 45% of maximal activity with maltotriitol as substrate, pH 7.0: about 70% of maximal activity with potato starch as substrate, about 65% of maximal activity with maltotriitol as substrate | Homo sapiens |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 5 | 9 | 4°C, 24 h, stable | Homo sapiens |
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Release 2023.1 (January 2023)
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