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Literature summary for 3.2.1.18 extracted from

  • Paolini, L.; Orizio, F.; Busatto, S.; Radeghieri, A.; Bresciani, R.; Bergese, P.; Monti, E.
    Exosomes secreted by hela cells shuttle on their surface the plasma membrane-associated sialidase NEU3 (2017), Biochemistry, 56, 6401-6408 .
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
exosome
-
Homo sapiens
-
-
plasma membrane
-
Homo sapiens 5886
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-methylumbelliferyl alpha-N-acetylneuraminic acid + H2O
-
Homo sapiens 4-methylumbelliferone + alpha-N-acetylneuraminic acid
-
?

Synonyms

Synonyms Comment Organism
Neu3
-
Homo sapiens

General Information

General Information Comment Organism
physiological function isoform NEU3 is involved in the fine-tuning of sialic acid-containing glycans directly on the cell surface and plays relevant roles in important biological phenomena such as cell differentiation, molecular recognition, and cancer transformation Homo sapiens