Cloned (Comment) | Organism |
---|---|
gene TS1, DNA and amino acid sequence determination and analysis, sequence comparisons | Trypanosoma congolense |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma congolense | Q7YZT3 | 11 isozymes of trans-sialidase 1, gene TS1 | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | nine potential N-glycosylation sites | Trypanosoma congolense |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | trans-sialidase 1 produces alpha2,3-sialyllactose from lactose by desialylating fetuin exhibiting transsialidase activity, substrate specificities for lactose, fetuin and synthetic substrates, overview. The enzyme is able to sialylate asialofetuin. Sialylation pattern of the N-glycans on fetuin catalyzed by the trans-sialidases, overview | Trypanosoma congolense | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | the enzyme possesses an N-terminal signal peptide and a catalytic domain, residues 17-467, which is connected through a long alpha helix, residues 468-491, to a lectin domain, residues 492-732, followed by a potential C-terminal GPI-anchor attachment site, residues 733-750 | Trypanosoma congolense |
Synonyms | Comment | Organism |
---|---|---|
trans-sialidase 1 | - |
Trypanosoma congolense |
General Information | Comment | Organism |
---|---|---|
additional information | trans-sialidase 1 model structure complexed with the Sia derivative 3-fluoro-5-N-acetyl-9-benzamido-2,9-dideoxy-neuraminic acid | Trypanosoma congolense |