Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EDTA | - |
influenza A virus | |
Zn2+ | slight inhibition | influenza A virus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetics | influenza A virus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | activates about 2fold, increase in initial reaction velocity, required | influenza A virus | |
Mg2+ | activates about 2fold, increase in initial reaction velocity, required | influenza A virus | |
additional information | decrease in activity through removal of divalent cations results in decreased immunogenicity, antibody response decreases by about 68-76%, 80% of the original activity is restored by addition of Ca2+ and Mg2+ | influenza A virus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
influenza A virus | - |
type N2, several strains | - |
Purification (Comment) | Organism |
---|---|
from several strains | influenza A virus |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
activity of different strains in presence or absence of divalent cations, overview | influenza A virus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid + H2O | - |
influenza A virus | 4-methylumbelliferol + alpha-D-N-acetylneuraminic acid | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NA | - |
influenza A virus |
neuraminidase | - |
influenza A virus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | influenza A virus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.9 | - |
assay at | influenza A virus |