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Literature summary for 3.2.1.18 extracted from
- Sialidase in rabbit blood (1994), Eur. J. Biochem., 221, 655-664.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Triton X-100 | - |
Oryctolagus cuniculus |  |
General Stability
| General Stability | Organism |
|---|---|
| labile towards freezing and thrawing | Oryctolagus cuniculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| dithiothreitol | - |
Oryctolagus cuniculus | |
| Fe2+ | - |
Oryctolagus cuniculus | |
| Fe3+ | - |
Oryctolagus cuniculus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.06 | - |
GM1 | - |
Oryctolagus cuniculus | |
| 0.09 | - |
GM3 | - |
Oryctolagus cuniculus | |
| 0.1 | - |
sialyl-alpha-2,3-lactose | - |
Oryctolagus cuniculus | |
| 0.11 | - |
GD1a | - |
Oryctolagus cuniculus | |
| 0.13 | - |
sialyl-alpha-2,6-lactose | - |
Oryctolagus cuniculus | |
| 0.18 | - |
GM1 | - |
Oryctolagus cuniculus | |
| 0.19 | - |
GD1b | - |
Oryctolagus cuniculus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| plasma membrane | - |
Oryctolagus cuniculus | 5886 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 48000 | - |
gel filtration | Oryctolagus cuniculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Oryctolagus cuniculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Oryctolagus cuniculus | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| 4°C, 2 days without any loss in activity | Oryctolagus cuniculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid + H2O | - |
Oryctolagus cuniculus | 4-methylumbelliferone + N-acetylneuraminic acid | - |
? | |
| ganglioside GD1a + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
| ganglioside GD1b + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
| ganglioside GM1 + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
| ganglioside GM3 + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
| sialyl-alpha-2,3-lactose + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
| sialyl-alpha-2,6-lactose + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 4.5 | - |
- |
Oryctolagus cuniculus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 3.5 | 5.5 | - |
Oryctolagus cuniculus |
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