Activating Compound | Comment | Organism | Structure |
---|---|---|---|
histidine-rich glycoprotein | GeneBank accession number: BAA21613. Directly interacts with platelet-derived heparanase and enhances its enzymatic activity | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9Y251 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood platelet | - |
Homo sapiens | - |
General Information | Comment | Organism |
---|---|---|
physiological function | histidine-rich glycoprotein interferes with heparanase binding to cell surface receptors, particularly heparan sulfate proteoglycans. Thus, the interaction between histidine-rich glycoprotein and heparanase can potentially regulate the role of heparanase in a variety of physiological and pathological conditions | Homo sapiens |