Literature summary for 3.2.1.166 extracted from

Navarro, F.P.; Fares, R.P.; Sanchez, P.E.; Nadam, J.; Georges, B.; Moulin, C.; Morales, A.; Pequignot, J.M.; Bezin, L.
Brain heparanase expression is up-regulated during postnatal development and hypoxia-induced neovascularization in adult rats (2008), J. Neurochem., 105, 34-45.

Search for more literature for 3.2.1.166

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	heparanase protein is mainly detected in neurons. Heparanase transcript and protein reach their greatest levels at early postnatal stages, in particular within the neocortex. At adulthood the increased heparanase transcript level correlates in the hippocampus with enhanced angiogenesis following repeated hypoxia exposures. Potential importance of heparanase in brain homeostasis	Rattus norvegicus	-
PC-12 cell	increased heparanase expression during NGF-induced neuronal differentiation in PC12 cells	Rattus norvegicus	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)