Any feedback?
Literature summary for 3.2.1.147 extracted from
- Identification of Asp174 and Asp175 as the Key Catalytic Residues of Human O-GlcNAcase by Functional Analysis of Site-Directed Mutants (2006), Biochemistry, 45, 3835-3844.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| D174A | generated mutant, shows no activity toward pNP-S-GlcNAc | Homo sapiens |
| D175A | generated mutant, D175A mutant shows significant activity toward pNP-S-GlcNAc | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrophenyl 2-acetamido-2-deoxy-1-thio-beta-D-glucopyranoside + H2O | - |
Homo sapiens | 4-nitrobenzenethiol + N-acetyl-D-glucosamine | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| thioglycosidase | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
