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Literature summary for 3.2.1.147 extracted from

  • Bourderioux, A.; Lefoix, M.; Gueyrard, D.; Tatibouet, A.; Cottaz, S.; Arzt, S.; Burmeister, W.P.; Rollin, P.
    The glucosinolate-myrosinase system. New insights into enzyme-substrate interactions by use of simplified inhibitors (2005), Org. Biomol. Chem., 3, 1872-1879.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
(2-sulfato)ethyl 1-thio-beta-D-glucopyranoside 10mM, 30% inhibition Sinapis alba
(3-sulfato)propyl 1-thio-beta -D-glucopyranoside IC50: 5 mM Sinapis alba
(3-sulfonato)propyl 1-thio-beta-D-glucopyranoside 10 mM, 15% inhibition Sinapis alba
additional information no inhibition at 10 mM 2'-sulfatophenyl-1-thio-beta-D-glucopyranoside Sinapis alba
S-(2-hydroxyethyl)phenylacetothiohydroximate-O-sulfate 10 mM, 23% inhibition Sinapis alba
S-(3-hydroxypropyl)phenylacetothiohydroximate-O -sulfate 1 mM, 70% inhibition. IC50: 0.44 mM Sinapis alba
S-(4-hydroxybutyl)phenylacetothiohydroximate-O-sulfate 1 mM, 88% inhibition. IC50: 0.25 mM Sinapis alba
S-ethyl phenylacetothiohydroximate-O -sulfate 1 mM, 67% inhibition. IC50: 0.58 mM Sinapis alba

Organism

Organism UniProt Comment Textmining
Sinapis alba P29736
-
-

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.25
-
1 mM, 88% inhibition. IC50: 0.25 mM Sinapis alba S-(4-hydroxybutyl)phenylacetothiohydroximate-O-sulfate
0.44
-
1 mM, 70% inhibition. IC50: 0.44 mM Sinapis alba S-(3-hydroxypropyl)phenylacetothiohydroximate-O -sulfate
0.58
-
1 mM, 67% inhibition. IC50: 0.58 mM Sinapis alba S-ethyl phenylacetothiohydroximate-O -sulfate
5
-
IC50: 5 mM Sinapis alba (3-sulfato)propyl 1-thio-beta -D-glucopyranoside