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Literature summary for 3.2.1.143 extracted from

  • Tanuma, S.i.; Endo, H.
    Purification and characterization of an (ADP-ribose)n glycohydrolase from human erythrocytes (1990), Eur. J. Biochem., 191, 57-63.
    View publication on PubMed
Search for more literature for 3.2.1.143

Inhibitors

Inhibitors Comment Organism Structure
ADP-ribose
-
 Homo sapiens
cAMP
-
 Homo sapiens
KCl
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0058
-
 (ADP-D-ribose)15
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
56000
-
 gel filtration Homo sapiens
59000
-
 1 * 59000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
poly(ADP-ribose)n + H2O Homo sapiens poly(ADP-ribose) glycohydrolase II may be involved in extranuclear de(ADP-ribosyl)n-ation, but not in membrane de-mono(ADP-ribosyl)ation ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
poly(ADP-ribose) glycohydrolase II Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
14
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(ADP-D-ribose)15 + H2O
-
 Homo sapiens (ADP-ribose)14 + ADP-D-ribose
-
 ?
poly(ADP-ribose)n + H2O
-
 Homo sapiens ADP-ribose
-
 ?
poly(ADP-ribose)n + H2O poly(ADP-ribose) glycohydrolase II may be involved in extranuclear de(ADP-ribosyl)n-ation, but not in membrane de-mono(ADP-ribosyl)ation Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 59000, SDS-PAGE Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
-
 Homo sapiens