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Literature summary for 3.2.1.14 extracted from

  • Huang, G.L.; Zahng, D.W.; Zhao, H.J.; Zhang, H.C.; Wang, P.G.
    Chemo-enzymatic synthesis of 1,4-oxazepanyl sugar as potent inhibitor of chitinase (2006), Bioorg. Med. Chem., 14, 2446-2449.
    View publication on PubMed
Search for more literature for 3.2.1.14

Inhibitors

Inhibitors Comment Organism Structure
(1E)-prop-1-en-1-yl 2-(acetylamino)-4-O-[(2R,5R,6R)-5-(acetylamino)-2-(hydroxymethyl)-1,3-oxazinan-6-yl]-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-beta-D-glucopyranoside potent inhibition, IC50 is 0.0047 mM, chemo-enzymatic synthesis via allyl penta-N-acetyl-chitopentaose using recombinant NodC from Mesorhizobium loti expressed in Escherichia coli, overview Serratia marcescens

Organism

Organism UniProt Comment Textmining
Serratia marcescens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
-
 Serratia marcescens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
allyl penta-N-acetyl-chitopentaose + H2O
-
 Serratia marcescens ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
18
-
 assay at Serratia marcescens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5
-
 assay at Serratia marcescens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0047
-
 potent inhibition, IC50 is 0.0047 mM, chemo-enzymatic synthesis via allyl penta-N-acetyl-chitopentaose using recombinant NodC from Mesorhizobium loti expressed in Escherichia coli, overview Serratia marcescens (1E)-prop-1-en-1-yl 2-(acetylamino)-4-O-[(2R,5R,6R)-5-(acetylamino)-2-(hydroxymethyl)-1,3-oxazinan-6-yl]-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-beta-D-glucopyranoside