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Literature summary for 3.2.1.113 extracted from
- Hepatitis B virus upregulates host expression of alpha-1,2-mannosidases via the PPARalpha pathway (2016), World J. Gastroenterol., 22, 9534-9543 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | the class I alpha-mannosidases can be used as drug targets to inhibit the demannosylation of HBV, thereby improving the binding of the virus to DC-SIGN and disrupting the immune tolerance to prevent and treat viral infection | Homo sapiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| up | hepatitis B virus upregulates host expression of class I alpha-1,2-mannosidases via the PPARalpha pathway. Hepatitis B virus increases the expression of alpha-mannosidases both in vitro and in vivo via activation of the PPARalpha pathway by its envelope protein | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | O60476 | - |
- |
| Homo sapiens | P33908 | - |
- |
| Homo sapiens | Q9NR34 | - |
- |
| Homo sapiens | Q9UKM7 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Hep-G2 cell | - |
Homo sapiens | - |
| Hep-G2/2.15 cell | - |
Homo sapiens | - |
| Hep-N10 cell | - |
Homo sapiens | - |
| HepAD38 cell | - |
Homo sapiens | - |
| hepatoma cell | HepG2, HepG2.2.15, AD38, and N10 | Homo sapiens | - |
| liver | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MAN1A1 | - |
Homo sapiens |
| MAN1A2 | - |
Homo sapiens |
| MAN1B1 | - |
Homo sapiens |
| MAN1C1 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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