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Literature summary for 3.2.1.113 extracted from

  • Lu, Y.; Xu, Y.Y.; Fan, K.Y.; Shen, Z.H.
    1-Deoxymannojirimycin, the alpha1,2-mannosidase inhibitor, induced cellular endoplasmic reticulum stress in human hepatocarcinoma cell 7721 (2006), Biochem. Biophys. Res. Commun., 344, 221-225.
    View publication on PubMed
Search for more literature for 3.2.1.113

Application

Application Comment Organism
drug development development of anti-cancer therapies Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
1-deoxymannojirimycin mannose analogue, specific inhibitor of alpha1,2-mannosidase. Focus on the effect of blocking alpha-mannosidases I in human hepatocarcinoma 7721 cells concerning with endoplasmic reticulum stress. Observed that 1-deoxymannojirimycin can also be a radical stimulus in inducing endoplasmic reticulum stress Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Homo sapiens 5783
-
Golgi apparatus
-
 Homo sapiens 5794
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
H-7721 cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
alpha1,2-mannosidase
-
 Homo sapiens