Protein Variants | Comment | Organism |
---|---|---|
additional information | removal of domain I (LPHDELTA1) results in a malfolded ER-localized protein. Enzyme without domain II (LPHDELTA2) is normally transported along the secretory pathway, but does not dimerize nor is enzymatically active. The lactase activity is not detectable in LPHDELTA1 and LPHDELTA2. Phlorizin hydrolase activity is only detectable in LPHDELTA2, albeit at substantially reduced levels of 4.3% | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P09848 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | membrane anchored type I glycoprotein | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
intestinal epithelium | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
lactase-phlorizin hydrolase | - |
Homo sapiens |
LPH | - |
Homo sapiens |