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Literature summary for 3.2.1.106 extracted from

  • Kosuge, T.; Tamura, T.; Nariuchi, H.; Toyoshima, S.
    Effect of inhibitors of glycopotein processing on cytokine secretion and production in anti CD3-stimulated T cells (2000), Biol. Pharm. Bull., 23, 1-5.
    View publication on PubMed
Search for more literature for 3.2.1.106

Inhibitors

Inhibitors Comment Organism Structure
1-deoxynojirimycin
-
 Mus musculus
additional information inhibitors of processing glucosidase enhances anti CD3-induced interleukin-2 production and cause an accumulation of glucose-containing high-mannose-type oligosaccharides and suppress the secretion of interleukin-4, interferon-gamma and interleukin-5. Processing inhibitors inhibit the N-linked oligosaccharide processing of cytokines, inhibition of processing enzyme glucosidase I induces a decreased secretion of cytokines with N-linked oligosaccharides Mus musculus
N-methyl-1-deoxynojirimycin
-
 Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Glc3Man9GlcNAc2 + H2O Mus musculus catalyzes initial step in post-glycosylation processing of cellular glycoprotein ?
-
 ?
Glc3Man9GlcNAc2 + H2O Mus musculus involved in first step of processing of oligosaccharides after transfer from dolichyl diphosphate to proteins ?
-
 ?
Glc3Man9GlcNAc2 + H2O Mus musculus involved in processing of asparagine-linked oligosaccharides ?
-
 ?
additional information Mus musculus catalyzes initial step in post-glycosylation processing of cellular glycoprotein ?
-
 ?
additional information Mus musculus involved in first step of processing of oligosaccharides after transfer from dolichyl diphosphate to proteins ?
-
 ?
additional information Mus musculus involved in processing of asparagine-linked oligosaccharides ?
-
 ?
additional information Mus musculus involved in the formation of high mannose and complex glycoproteins ?
-
 ?
additional information Mus musculus C57BL/6 catalyzes initial step in post-glycosylation processing of cellular glycoprotein ?
-
 ?
additional information Mus musculus C57BL/6 involved in first step of processing of oligosaccharides after transfer from dolichyl diphosphate to proteins ?
-
 ?
additional information Mus musculus C57BL/6 involved in processing of asparagine-linked oligosaccharides ?
-
 ?
additional information Mus musculus C57BL/6 involved in the formation of high mannose and complex glycoproteins ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 female C57BL/6
-
Mus musculus C57BL/6
-
 female C57BL/6
-

Source Tissue

Source Tissue Comment Organism Textmining
spleen
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Glc3Man9GlcNAc2 + H2O
-
 Mus musculus D-glucose + Glc2Man9GlcNAc2
-
 ?
Glc3Man9GlcNAc2 + H2O
-
 Mus musculus C57BL/6 D-glucose + Glc2Man9GlcNAc2
-
 ?
Glc3Man9GlcNAc2 + H2O catalyzes initial step in post-glycosylation processing of cellular glycoprotein Mus musculus ?
-
 ?
Glc3Man9GlcNAc2 + H2O involved in first step of processing of oligosaccharides after transfer from dolichyl diphosphate to proteins Mus musculus ?
-
 ?
Glc3Man9GlcNAc2 + H2O involved in processing of asparagine-linked oligosaccharides Mus musculus ?
-
 ?
additional information catalyzes initial step in post-glycosylation processing of cellular glycoprotein Mus musculus ?
-
 ?
additional information involved in first step of processing of oligosaccharides after transfer from dolichyl diphosphate to proteins Mus musculus ?
-
 ?
additional information involved in processing of asparagine-linked oligosaccharides Mus musculus ?
-
 ?
additional information involved in the formation of high mannose and complex glycoproteins Mus musculus ?
-
 ?
additional information catalyzes initial step in post-glycosylation processing of cellular glycoprotein Mus musculus C57BL/6 ?
-
 ?
additional information involved in first step of processing of oligosaccharides after transfer from dolichyl diphosphate to proteins Mus musculus C57BL/6 ?
-
 ?
additional information involved in processing of asparagine-linked oligosaccharides Mus musculus C57BL/6 ?
-
 ?
additional information involved in the formation of high mannose and complex glycoproteins Mus musculus C57BL/6 ?
-
 ?