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Literature summary for 3.2.1.1 extracted from

  • Karthic, K.; Kirthiram, K.S.; Sadasivam, S.; Thayumanavan, B.
    Identification of alpha amylase inhibitors from Syzygium cumini Linn seeds (2008), Indian J. Exp. Biol., 46, 677-680.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
3,4',5,7-tetrahydroxyflavanone identified in the Sysygium cumini seed extract which results in 98% inhibition compared to control without the addition of medicinal plant extract, non-competitive inhibition determined by a Dixon plot, pH 6.9 Sus scrofa
Acalpha indica leaf extract herbal medicine for the treatment of diabetes in Ayurvedic system of medicine, 15% relative inhibition compared to control without the addition of medicinal plant extract, non-competitive inhibition determined by a Dixon plot, pH 6.9 Sus scrofa
Aegle marmelos leaf extract herbal medicine for the treatment of diabetes in Ayurvedic system of medicine, 6% relative inhibition compared to control without the addition of medicinal plant extract, non-competitive inhibition determined by a Dixon plot, pH 6.9 Sus scrofa
betulinic acid identified in the Sysygium cumini seed extract which results in 98% inhibition compared to control without the addition of medicinal plant extract, non-competitive inhibition determined by a Dixon plot, pH 6.9 Sus scrofa
Gymnema sylvestre leaf extract herbal medicine for the treatment of diabetes in Ayurvedic system of medicine, 3% relative inhibition compared to control without the addition of medicinal plant extract, non-competitive inhibition determined by a Dixon plot, pH 6.9 Sus scrofa
Limonia acidissimia seed extract herbal medicine for the treatment of diabetes in Ayurvedic system of medicine, 20% relative inhibition compared to control without the addition of medicinal plant extract, non-competitive inhibition determined by a Dixon plot, pH 6.9 Sus scrofa
additional information no inhibition with Murraya koenigii leaf extract Sus scrofa
Moringa oleifera leaf extract herbal medicine for the treatment of diabetes in Ayurvedic system of medicine, 16% relative inhibition compared to control without the addition of medicinal plant extract, non-competitive inhibition determined by a Dixon plot, pH 6.9 Sus scrofa
Psidium guajava var. Pomiferum leaf extract herbal medicine for the treatment of diabetes in Ayurvedic system of medicine, 98% relative inhibition compared to control without the addition of medicinal plant extract, non-competitive inhibition determined by a Dixon plot, pH 6.9 Sus scrofa
Sysygium cumini seed extract herbal medicine for the treatment of diabetes in Ayurvedic system of medicine, phenolics, terpenoids, and alkaloids are identified, mass spectrometry revlealed the presence of betulinic acid and 3,5,7,4'-tetrahydroxyflavanone, 98% relative inhibition compared to control without the addition of medicinal plant extract, non-competitive inhibition determined by a Dixon plot, pH 6.9 Sus scrofa
Tinospora cordifolia leaf extract herbal medicine for the treatment of diabetes in Ayurvedic system of medicine, 13% relative inhibition compared to control without the addition of medicinal plant extract, non-competitive inhibition determined by a Dixon plot, pH 6.9 Sus scrofa
Trigonella foenum graecum seed extract herbal medicine for the treatment of diabetes in Ayurvedic system of medicine, 10% relative inhibition compared to control without the addition of medicinal plant extract, non-competitive inhibition determined by a Dixon plot, pH 6.9 Sus scrofa
Zizyphus mauritiana seed extract herbal medicine for the treatment of diabetes in Ayurvedic system of medicine, 12% relative inhibition compared to control without the addition of medicinal plant extract, non-competitive inhibition determined by a Dixon plot, pH 6.9 Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
commercial preparation
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreas
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
starch + H2O inhibition studies using extract of different medicinal plants, pH 6.9 Sus scrofa ? absorbance of reaction products are measured at 540 nm ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.9
-
assay at Sus scrofa