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Literature summary for 3.11.1.2 extracted from

  • Villarreal-Chiu, J.F.; Quinn, J.P.; McGrath, J.W.
    The genes and enzymes of phosphonate metabolism by bacteria, and their distribution in the marine environment (2012), Front. Microbiol., 3, 19.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene phnA, the gene is encoded within an operon whose expression is regulated by a phosphonoacetate-responsive LTTR Pseudomonas fluorescens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Phosphonoacetate + H2O Pseudomonas fluorescens
-
acetate + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Pseudomonas fluorescens Q51782 gene phnA
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information the organism is capable of utilizing phosphonoacetate as sole C and P source Pseudomonas fluorescens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Phosphonoacetate + H2O
-
Pseudomonas fluorescens acetate + phosphate
-
?
Phosphonoacetate + H2O metal-assisted hydrolytic cleavage of the C-P bond Pseudomonas fluorescens acetate + phosphate
-
?

General Information

General Information Comment Organism
evolution the enzyme is a member of the alkaline phosphatase superfamily. Distributionof phnX homologs within sequenced bacterial genomes, overview Pseudomonas fluorescens
metabolism catabolic C-P-bond metabolism in bacteria, and the pathways for the microbial metabolism of phosphonates, overview. The enzyme is involved in the phosphonoacetate catabolism Pseudomonas fluorescens