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Literature summary for 3.10.1.1 extracted from

  • Savas, P.S.; Hemsley, K.M.; Hopwood, J.J.
    Intracerebral injection of sulfamidase delays neuropathology in murine MPS-IIIA (2004), Mol. Genet. Metab., 82, 273-285.
    View publication on PubMed

Application

Application Comment Organism
medicine intracerebral injection of recombinant human sulfamidase delays neuropathology in murine MPS-IIIA. Treatment reduces vacuolation and gliosis and delays the onset of ubiquitin-positive neurodegenerative changes in widespread areas of mucopolysaccharidosis type IIA brain, assessed at 24 weeks of age Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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