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Literature summary for 3.1.99.B1 extracted from

  • Fortini, B.K.; Pokharel, S.; Polaczek, P.; Balakrishnan, L.; Bambara, R.A.; Campbell, J.L.
    Characterization of the endonuclease and ATP-dependent flap endo/exonuclease of Dna2 (2011), J. Biol. Chem., 286, 23763-23770.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.99.B1

Inhibitors

Inhibitors Comment Organism Structure
ATP inhibits the flap endo/exonuclease activity of Dna2 Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Homo sapiens
Mn2+ required Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
M13mp18 circular ssDNA + H2O
-
 Homo sapiens ?
-
 ?
Phi X174 circular ssDNA + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
Dna2
-
 Homo sapiens
flap endonuclease 1
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Homo sapiens