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Literature summary for 3.1.8.1 extracted from
- Paraoxonase 1 Q192R genotype and activity affect homocysteine thiolactone levels in humans (2018), FASEB J., 32, 6019 .
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| Q192R | the mutant exhibits significantly lower homocysteine-thiolactone/creatinine levels and has 2.6 and 3.3fold greater catalytic efficiency with homocysteine-thiolactone and paraoxon, respectively, than the wild type enzyme | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood serum | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| paraoxon + H2O | - |
Homo sapiens | 4-nitrophenol + diethyl phosphate | - |
? |  |
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Release 2023.1 (January 2023)
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