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Literature summary for 3.1.8.1 extracted from

  • Valiyaveettil, M.; Alamneh, Y.; Rezk, P.; Biggemann, L.; Perkins, M.W.; Sciuto, A.M.; Doctor, B.P.; Nambiar, M.P.
    Protective efficacy of catalytic bioscavenger, paraoxonase 1 against sarin and soman exposure in guinea pigs (2011), Biochem. Pharmacol., 81, 800-809.
    View publication on PubMed
Search for more literature for 3.1.8.1

Application

Application Comment Organism
medicine paraoxonase 1 significantly protects against sarin and soman exposure in guinea pigs and supports the development of paraoxonase 1 as a catalytic bioscavenger for protection against lethal exposure of chemical warfare nerve agents exposure Homo sapiens
medicine paraoxonase 1 significantly protects against sarin and soman exposure in guinea pigs and supports the development of paraoxonase 1 as a catalytic bioscavenger for protection against lethal exposure of chemical warfare nerve agents exposure Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Oryctolagus cuniculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens
-
 Oryctolagus cuniculus

Source Tissue

Source Tissue Comment Organism Textmining
serum
-
 Homo sapiens
-
serum
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
paraoxon + H2O
-
 Homo sapiens 4-nitrophenol + diethyl phosphate
-
 ?
paraoxon + H2O
-
 Oryctolagus cuniculus 4-nitrophenol + diethyl phosphate
-
 ?
sarin + H2O
-
 Homo sapiens ?
-
 ?
sarin + H2O
-
 Oryctolagus cuniculus ?
-
 ?
soman + H2O
-
 Homo sapiens ?
-
 ?
soman + H2O
-
 Oryctolagus cuniculus ?
-
 ?