Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ascorbate | 0.5 mM inhibits by ca. 22%. Ascorbate/Cu2+ (0.5 mM/0.001 mM) system shows ca. 63% inactivation | Homo sapiens | |
Cu2+ | Cu2+ alone has no effect. Ascorbate/Cu2+ (0.5 mM/0.001 mM) system shows ca. 63% inactivation | Homo sapiens | |
Fe2+ | ascorbate/Fe2+ (0.5 mM/0.002 mM) system shows ca. 27% inactivation after 30 min | Homo sapiens | |
additional information | 1 mM 3-morpholinosydnoimine, 0.002 mM Fe2+ or 0.01 mM Mn2+, Co2+, Zn2+, or 0.001 mM Cu2+ cause no significant loss of activity | Homo sapiens | |
sodium hypochlorite | at 1 mM and in the presence of PBS buffer causes approximately 49% decrease in activity | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | required for the catalysis | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
45000 | - |
x * 45000, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
by different types of chromatographies | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
plasma | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.391 | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
paraoxon + H2O | - |
Homo sapiens | 4-nitrophenol + diethyl phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 45000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
paraoxonase 1 | - |
Homo sapiens |
PON1 | - |
Homo sapiens |