Application | Comment | Organism |
---|---|---|
analysis | PON1 status can be used as a potential biomarker for insecticides metabolites in urine, e.g. dimethyl phosphate and diethyl phosphate, and of susceptibility to organophosphate toxicity, overview | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | analysis of PON1 polymorphisms, e.g. at residue Q192R, overview | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | secreted from the liver into the blood serum | Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme is important in detoxification of organophosphorus compounds, structure and applications of organophosphorus compounds, clinical evidence of PON1, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
serum | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
diazoxon + H2O | - |
Homo sapiens | 6-methyl-2-(1-methylethyl)pyrimidin-4-ol + diethyl phosphate | - |
ir | |
additional information | the enzyme is important in detoxification of organophosphorus compounds, structure and applications of organophosphorus compounds, clinical evidence of PON1, overview | Homo sapiens | ? | - |
? | |
paraoxon + H2O | - |
Homo sapiens | 4-nitrophenol + diethyl phosphate | - |
ir |
Synonyms | Comment | Organism |
---|---|---|
paraoxonase | - |
Homo sapiens |
PON1 | - |
Homo sapiens |