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Literature summary for 3.1.8.1 extracted from
- Organophosphate hydrolase - an enzyme catalyzing degradation of phosphorus-containing toxins and pesticides (2001), Russ. Chem. Bull. (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya), 50, 1826-1832.
No PubMed abstract available
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | Km values of paraoxon hydrolysis with different metal ions in the active site | Flavobacterium sp. | |
| additional information | - |
additional information | Km values of paraoxon hydrolysis with different metal ions in the active site | Brevundimonas diminuta |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Co2+ | 2 Zn2+ or Co2+ ions per subunit | Flavobacterium sp. |  |
| Co2+ | 2 Zn2+ or Co2+ ions per subunit | Brevundimonas diminuta | |
| Zn2+ | 2 Zn2+ or Co2+ ions per subunit | Flavobacterium sp. | |
| Zn2+ | 2 Zn2+ or Co2+ ions per subunit | Brevundimonas diminuta | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Brevundimonas diminuta | - |
- |
- |
| Flavobacterium sp. | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| an aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol | kinetics and mechanism | Flavobacterium sp. | |
| an aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol | kinetics and mechanism | Brevundimonas diminuta |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acephate + H2O | - |
Flavobacterium sp. | ? | - |
? | |
| acephate + H2O | - |
Brevundimonas diminuta | ? | - |
? | |
| coumaphos + H2O | - |
Flavobacterium sp. | ? | - |
? | |
| demethon-S + H2O | - |
Flavobacterium sp. | ? | - |
? | |
| demethon-S + H2O | - |
Brevundimonas diminuta | ? | - |
? | |
| malathion + H2O | - |
Flavobacterium sp. | ? | - |
? | |
| malathion + H2O | - |
Brevundimonas diminuta | ? | - |
? | |
| methyl parathion + H2O | - |
Flavobacterium sp. | ? | - |
? | |
| methyl parathion + H2O | - |
Brevundimonas diminuta | ? | - |
? | |
| additional information | overview on substrate specificity | Flavobacterium sp. | ? | - |
? | |
| additional information | overview on substrate specificity | Brevundimonas diminuta | ? | - |
? | |
| parathion + H2O | - |
Flavobacterium sp. | ? | - |
? | |
| parathion + H2O | - |
Brevundimonas diminuta | ? | - |
? | |
| sarin + H2O | - |
Rattus norvegicus | ? | - |
? | |
| sarin + H2O | - |
Flavobacterium sp. | ? | - |
? | |
| sarin + H2O | - |
Brevundimonas diminuta | ? | - |
? | |
| soman + H2O | - |
Rattus norvegicus | ? | - |
? | |
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