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Literature summary for 3.1.7.6 extracted from

  • Ha, S.B.; Lee, D.E.; Lee, H.J.; Song, S.J.; Back, K.
    Activities of soluble and microsomal farnesyl diphosphatases in Datura stramonium (2003), Biol. Plant., 47, 477-479.
No PubMed abstract available

Activating Compound

Activating Compound Comment Organism Structure
ATP 0.05, 8% stimulation Datura stramonium
isopentenyl diphosphate 20% stimulation of soluble enzyme at 0.1 mM, 20% stimulation of microsomal enzyme at 0.02 mM Datura stramonium
p-nitrophenyl phosphate 0.05, 10% stimulation Datura stramonium

Inhibitors

Inhibitors Comment Organism Structure
geranyl diphosphate 16% inhibition of soluble enzyme at 0.1 mM. 26% inhibition of microsomal enzyme at 0.05 mM Datura stramonium
geranylgeranyl diphosphate 0.05 mM, 16% inhibition of soluble enzyme, 38% inhibition of microsomal enzyme Datura stramonium

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome constitutively expressed at a high level in the soluble and the microsomal fraction Datura stramonium
-
-
soluble constitutively expressed at a high level in the soluble and the microsomal fraction Datura stramonium
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
additional information Mg2+-independent enzyme Datura stramonium

Organism

Organism UniProt Comment Textmining
Datura stramonium
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
flower soluble farnesyl diphosphatase is highest in fruit and flower followed by root and leaf Datura stramonium
-
fruit soluble farnesyl diphosphatase is highest in fruit and flower followed by root and leaf Datura stramonium
-
leaf soluble farnesyl diphosphatase is highest in fruit and flower followed by root and leaf Datura stramonium
-
root soluble farnesyl diphosphatase is highest in fruit and flower followed by root and leaf. Root has the highest level of microsomal enzyme Datura stramonium
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2E,6E)-farnesyl diphosphate + H2O
-
Datura stramonium (2E,6E)-farnesol + diphosphate diphosphate not determined ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.2
-
microsomal enzyme Datura stramonium
6
-
soluble enzyme Datura stramonium

pH Range

pH Minimum pH Maximum Comment Organism
4.5 6.8 pH 4.5: about 55% of maximal activity, pH 6.8: about 60% of maximal activit, soluble enzyme Datura stramonium
5 6.8 pH 5.0: about 60% of maximal activity, pH 6.8: about 65% of maximal activit, microsomal enzyme Datura stramonium

Expression

Organism Comment Expression
Datura stramonium constitutively expressed at a high level in the soluble and the microsomal fraction up