Literature summary for 3.1.7.2 extracted from

Lee, J.W.; Park, Y.H.; Seok, Y.J.
Rsd balances (p)ppGpp level by stimulating the hydrolase activity of SpoT during carbon source downshift in Escherichia coli (2018), Proc. Natl. Acad. Sci. USA, 115, E6845-E6854 .

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Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	P0AG24	bifunctional (p)ppGpp synthase/hydrolase SpoT, catalyzes reactions of EC 2.7.6.5 and EC 3.1.7.2	-

General Information

General Information	Comment	Organism
physiological function	anti-sigma factor Rsd directly interacts with SpoT and stimulates its (p)ppGpp hydrolase activity. Dephosphorylated histidine-containing phosphocarrier protein HPr of the phosphoenolpyruvate-dependent sugar phosphotransferase system can antagonize the stimulatory effect of Rsd on SpoT (p)ppGpp hydrolase activity	Escherichia coli

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Release 2023.1 (January 2023)