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Literature summary for 3.1.7.2 extracted from

  • Ronneau, S.; Caballero-Montes, J.; Coppine, J.; Mayard, A.; Garcia-Pino, A.; Hallez, R.
    Regulation of (p)ppGpp hydrolysis by a conserved archetypal regulatory domain (2019), Nucleic Acids Res., 47, 843-854 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Caulobacter vibrioides A0A0H3C9W6 bifunctional (p)ppGpp synthase/hydrolase SpoT, catalyzes reactions of EC 2.7.6.5 and EC 3.1.7.2
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Caulobacter vibrioides NA1000 A0A0H3C9W6 bifunctional (p)ppGpp synthase/hydrolase SpoT, catalyzes reactions of EC 2.7.6.5 and EC 3.1.7.2
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General Information

General Information Comment Organism
physiological function SpoT requires the ACT domain to efficiently hydrolyze (p)ppGpp. The phosphorylated version of EIIANtr interacts directly with the ACT and inhibits the hydrolase activity of SpoT Caulobacter vibrioides