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Literature summary for 3.1.7.2 extracted from

  • Murray, K.D.; Bremer, H.
    Control of spoT-dependent ppGpp synthesis and degradation in Escherichia coli (1996), J. Mol. Biol., 259, 41-57.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Uncharged tRNA the ppGpp hydrolase activity is controlled by the concentration of uncharged tRNA Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ppGpp + H2O Escherichia coli the enzyme may be a bifunctional protein catalyzing either ppGpp synthesis or degradation ppG + diphosphate
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?

Organism

Organism UniProt Comment Textmining
Escherichia coli
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ppGpp + H2O i.e. guanosine-3',5'-bis(diphosphate) Escherichia coli ppG + diphosphate i.e. guanosine 5'-diphosphate ?
ppGpp + H2O the enzyme may be a bifunctional protein catalyzing either ppGpp synthesis or degradation Escherichia coli ppG + diphosphate
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?