Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.6.8 extracted from

  • Nicholls, R.G.; Roy, A.B.
    Arylsulfatases (1971), The Enzymes, 3rd Ed. (Boyer, P. D. , ed. ), 5, 21-41.
No PubMed abstract available
Search for more literature for 3.1.6.8

Inhibitors

Inhibitors Comment Organism Structure
Ag+
-
 Bos taurus
Cu2+
-
 Bos taurus
hydrazine
-
 Bos taurus
hydroxylamine
-
 Bos taurus
K2SO4
-
 Bos taurus
p-hydroxymercuribenzoate
-
 Bos taurus
SO42-
-
 Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.47
-
 2-hydroxy-5-nitrophenyl sulfate
-
 Bos taurus
0.76
-
 pyridyl 4-sulfate
-
 Bos taurus
4.4
-
 2-nitropyridyl 3-sulfate
-
 Bos taurus
6.5
-
 2-nitrophenyl sulfate
-
 Bos taurus
9.5
-
 phenanthryl sulfate
-
 Bos taurus
31
-
 pyridyl 3-sulfate
-
 Bos taurus
38
-
 2-hydroxyphenyl sulfate
-
 Bos taurus
53
-
 4-nitrophenyl sulfate
-
 Bos taurus
53
-
 Naphthyl sulfate
-
 Bos taurus
63
-
 5,6,7,8-tetrahydro-2-naphthyl sulfate
-
 Bos taurus
77
-
 3-nitrophenyl sulfate
-
 Bos taurus
310
-
 phenyl sulfate
-
 Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cerebroside 3-sulfate + H2O Bos taurus
-
 cerebroside + sulfate
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Bos taurus

Reaction

Reaction Comment Organism Reaction ID
a cerebroside 3-sulfate + H2O = a cerebroside + sulfate hydrolyses galactose-3-sulfate residues in a number of lipids, also hydrolyses ascorbate 2-sulfate and many phenol sulfates, enzymes catalyze in addition to reaction of EC 3.1.6.8 also arylsulfatase reaction EC 3.1.6.1 Bos taurus
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-hydroxy-5-nitrophenyl sulfate + H2O
-
 Bos taurus 2-hydroxy-5-nitrophenol + sulfate
-
 ?
2-hydroxyphenyl sulfate + H2O
-
 Bos taurus 2-hydroxyphenol + sulfate
-
 ?
2-naphthyl sulfate + H2O
-
 Bos taurus 2-naphthol + sulfate
-
 ?
2-nitrophenyl sulfate + H2O
-
 Bos taurus 2-nitrophenol + sulfate
-
 ?
2-nitropyridyl 3-sulfate + H2O
-
 Bos taurus 2-nitropyridin-3-ol + sulfate
-
 ?
3-nitrophenyl sulfate + H2O
-
 Bos taurus 3-nitrophenol + sulfate
-
 ?
4-nitrophenyl sulfate + H2O
-
 Bos taurus 4-nitrophenol + sulfate
-
 ?
5,6,7,8-tetrahydro-2-naphthyl sulfate + H2O
-
 Bos taurus 5,6,7,8-tetrahydro-2-naphthol + sulfate
-
 ?
cerebroside 3-sulfate + H2O
-
 Bos taurus cerebroside + sulfate
-
 ?
naphthyl sulfate + H2O
-
 Bos taurus naphthol + sulfate
-
 ?
nitrocatechol sulfate + H2O
-
 Bos taurus nitrocatechol + sulfate
-
 ?
phenanthryl sulfate + H2O
-
 Bos taurus phenanthrol + sulfate
-
 ?
phenyl sulfate + H2O
-
 Bos taurus phenol + sulfate
-
 ?
pyridyl 3-sulfate + H2O
-
 Bos taurus pyridol + sulfate
-
 ?
pyridyl 4-sulfate + H2O
-
 Bos taurus pyridol + sulfate
-
 ?

Subunits

Subunits Comment Organism
dimer between pH 5.5-6.5, depends also on ionic strength Bos taurus
monomer at pH 5.6 monomer, at pH 4.8 tetramer Bos taurus

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
65
-
 5 min, no loss of activity Bos taurus