Application | Comment | Organism |
---|---|---|
medicine | estrone sulfatase is a target enzyme in the treatment of hormone-dependent breast cancer | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | design and synthesis of steroidal and nonsteroidal enzyme inhibitors as sulfamate derivatives and nonsulfamate derivatives, overview | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
estrone sulfate + H2O | Homo sapiens | - |
estrone + sulfate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast cancer cell | hormone-dependent | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
estrone sulfate + H2O | - |
Homo sapiens | estrone + sulfate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
estrone sulfatase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
metabolism | conversion of estrone sulfate to estrone is a non-aromatase-based route to estrone and estradiol in postmenopausal women | Homo sapiens |