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Literature summary for 3.1.6.13 extracted from

  • Parkinson-Lawrence, E.; Turner, C.; Hopwod, J.; Brooks, D.
    Analysis of normal and mutant iduronate-2-sulphatase conformation (2005), Biochem. J., 386, 395-400.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.6.13

Application

Application Comment Organism
medicine monoclonal antibodies demonstrate the capacity to differentiate progressive structural changes in iduronate-2-sulphatase and can be used to characterize the severity of mucopolysaccharidosis type II in patients based on variable denatured microstates Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens involved in the degradation of the glycosaminoglycans heparan sulfate and dermatan sulfate. An enzyme deficiency causes the lysosomal storage disorder muco-polysaccharidosis type II ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P22304
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information involved in the degradation of the glycosaminoglycans heparan sulfate and dermatan sulfate. An enzyme deficiency causes the lysosomal storage disorder muco-polysaccharidosis type II Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
iduronate-2-sulphatase
-
 Homo sapiens