Literature summary for 3.1.6.12 extracted from

Ruane, T.; Haskins, M.; Cheng, A.; Wang, P.; Aguirre, G.; Knox, V.W.; Qi, Y.; Tompkins, T.; ONeill, C.A.
Pharmacodynamics, pharmacokinetics and biodistribution of recombinant human N-acetylgalactosamine 4-sulfatase after 6 months of therapy in cats using different IV infusion durations (2016), Mol. Genet. Metab., 117, 157-163 .

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Application

Application	Comment	Organism
medicine	administration of recombinant enzyme as 2- and 4-h intravenous infusions using a feline model of mucopolysaccharidosis VI does not lead to significant differences in clinical outcomes such as urinary glycosaminoglycan excretion, tissue glycosaminoglycan storage, tissue galsulfase activity, and beta-glucuronidase but all are significantly different to control animals	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P15848	-	-

Synonyms

Synonyms	Comment	Organism
ASB	-	Homo sapiens

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Release 2023.1 (January 2023)