Protein Variants | Comment | Organism |
---|---|---|
additional information | ASB silencing in IB3-1 and C38 bronchial epithelial cell lines and in primary bronchial epithelial cells, leading to reduced ASB activity, chondroitin 4-sulfate content, and increased interleukin-8 content associated to the cell membranes instead of secreted. Neutrophil attraction to the cell lysate is increased in ABS silencing, overview | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cell membrane | - |
Homo sapiens | - |
- |
lysosome | - |
Homo sapiens | 5764 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
C38 cell | - |
Homo sapiens | - |
epithelial cell | bronchial | Homo sapiens | - |
IB3-1 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-methylumbelliferyl sulfate + H2O | - |
Homo sapiens | 4-methylumbelliferone + sulfate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
arylsulfatase B | - |
Homo sapiens |
ASB | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.6 | - |
assay at | Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | ASB and chondroitin 4-sulafte are involved in regulation of interleukin-8 secretion | Homo sapiens |