Any feedback?
Literature summary for 3.1.6.12 extracted from
- Maroteaux-Lamy disease (mucopolysaccharidosis VI), subtype A: deficiency of a N-acetylgalactosamine-4-sulfatase (1974), Biochem. Biophys. Res. Commun., 60, 1170-1177.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | deficiency in Maroteaux-Lamy syndrome, mucopolysaccharidosis type IV | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N-acetyl-D-galactosamine 4-sulfate units + H2O | Homo sapiens | acts also on N-acetylglucosamine 4-sulfate | N-acetyl-D-galactosamine units + sulfate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| skin | cultured fibroblasts | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dermatan sulfate + H2O | reduced activity in patients with Maroteaux-Lamy Syndrome | Homo sapiens | dermatan + sulfate | - |
? | |
| N-acetyl-D-galactosamine 4-sulfate units + H2O | acts also on N-acetylglucosamine 4-sulfate | Homo sapiens | N-acetyl-D-galactosamine units + sulfate | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
