Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ag+ | not | Mus musculus | |
Ba2+ | not; slight | Mus musculus | |
Na2HPO4 | - |
Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.3 | - |
p-nitrocatechol sulfate | - |
Mus musculus | |
4 | - |
4-Methylumbelliferyl sulfate | pH 5.5 | Mus musculus | |
5.6 | - |
4-Methylumbelliferyl sulfate | - |
Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Mus musculus | 5764 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50000 | - |
1 * 50000, SDS-PAGE, gel filtration | Mus musculus |
55000 | - |
gel filtration | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-D-galactosamine 4-sulfate units + H2O | Mus musculus | acts also on N-acetylglucosamine 4-sulfate | N-acetyl-D-galactosamine units + sulfate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
3 strains: C57BL/6J, SWR/J and A/J | - |
Purification (Comment) | Organism |
---|---|
- |
Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
30.7 | - |
strain A/J | Mus musculus |
59.55 | - |
strain SWR/J | Mus musculus |
67.53 | - |
strain C57BL/6J | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-methylumbelliferyl sulfate + H2O | - |
Mus musculus | 4-methylumbelliferone + sulfate | - |
? | |
chondroitin 4-sulfate + H2O | - |
Mus musculus | chondroitin + sulfate | - |
? | |
chondroitin 4-sulfate-heptasaccharide + H2O | - |
Mus musculus | chondroitin 4-sulfate-heptasaccharide + sulfate | - |
? | |
dermatan sulfate + H2O | - |
Mus musculus | dermatan + sulfate | - |
? | |
N-acetyl-D-galactosamine 4-sulfate + H2O | - |
Mus musculus | N-acetyl-D-galactosamine + sulfate | - |
? | |
N-acetyl-D-galactosamine 4-sulfate units + H2O | acts also on N-acetylglucosamine 4-sulfate | Mus musculus | N-acetyl-D-galactosamine units + sulfate | - |
? | |
p-nitrocatechol sulfate + H2O | enzymes catalyze in addition to reaction of EC 3.1.6.12 also arylsulfatase reaction , see also EC 3.1.6.1 | Mus musculus | p-nitrocatechol + sulfate | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 50000, SDS-PAGE, gel filtration | Mus musculus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
60 | - |
pH 5.9 | Mus musculus |
60 | - |
20 min | Mus musculus |
65 | - |
19 min | Mus musculus |
65 | - |
t1/2 of A/J enzyme: 20 min | Mus musculus |
65 | - |
t1/2 of SWR/J enzyme: 46 min | Mus musculus |