Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.6.11 extracted from

  • Weissmann, B.; Chao, H.; Chow, P.
    A glucosamine O,N-disulfate O-sulfohydrolase with a probable role in mammalian catabolism of heparan sulfate (1980), Biochem. Biophys. Res. Commun., 97, 827-833.
    View publication on PubMed
Search for more literature for 3.1.6.11

Inhibitors

Inhibitors Comment Organism Structure
NaCl 0.16 M 50% inhibition Bos taurus
PO43- 0.2 mM 22% inhibition Bos taurus
SO32- 0.2 mM 97% inhibition Bos taurus
SO42- 0.2 mM 43% inhibition Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
heparan sulfate + H2O Bos taurus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
 cow
-

Purification (Commentary)

Purification (Comment) Organism
partial Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(glucosamine O,N-disulfate)-(iduronic acid O-sulfate)-(3H-anhydromannitol O-sulfate) + H2O substrate prepared from degradation products of heparin Bos taurus ?
-
 ?
heparan sulfate + H2O
-
 Bos taurus ?
-
 ?
methyl glycoside 6-O-sulfate + H2O
-
 Bos taurus ?
-
 ?
methyl-2-sulfamino2-deoxy-alpha-D-glucopyranoside 3-sulfate + H2O
-
 Bos taurus ?
-
 ?
methyl-2-sulfamino2-deoxy-alpha-D-glucopyranoside 6-sulfate + H2O
-
 Bos taurus ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1
-
-
 Bos taurus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.16
-
 NaCl
-
 Bos taurus