Literature summary for 3.1.5.B1 extracted from

Choi, J.; Ryoo, J.; Oh, C.; Hwang, S.; Ahn, K.
SAMHD1 specifically restricts retroviruses through its RNase activity (2015), Retrovirology, 12, 46 .

Search for more literature for 3.1.5.B1

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9Y3Z3	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
macrophage	-	Homo sapiens	-

General Information

General Information	Comment	Organism
physiological function	SAMHD1 also acts as a nuclease, specifically degrading retroviral genomic RNA in monocyte-derived macrophage-like cells and in primary monocyte-derived macrophages. SAMHD1 selectively restricts retroviral replication, but does not affect the replication of other common non-retro RNA genome viruses	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)