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Literature summary for 3.1.5.1 extracted from

  • Wurgler, S.M.; Richardson, C.C.
    DNA binding properties of the deoxyguanosine triphosphate triphosphohydrolase of Escherichia coli (1993), J. Biol. Chem., 268, 20046-20054.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
NaCl inhibition of binding to single or double stranded DNA Escherichia coli

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.002 0.005 dGTP
-
Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ enhances DNA binding but not required Escherichia coli
Mn2+ enhance DNA binding but not required Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dGTP + H2O Escherichia coli
-
deoxyguanosine + triphosphate
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
high affinity for DNA Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dGTP + H2O
-
Escherichia coli deoxyguanosine + triphosphate
-
?
dGTP + H2O highly specific for Escherichia coli deoxyguanosine + triphosphate
-
?