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BRENDA support

Literature summary for 3.1.4.53 extracted from

  • Huang, Y.M.; Huber, G.; McCammon, J.A.
    Electrostatic steering enhances the rate of cAMP binding to phosphodiesterase Brownian dynamics modeling (2015), Protein Sci., 24, 1884-1889 .
    View publication on PubMedView publication on EuropePMC

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ required Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3',5'-cAMP + H2O Homo sapiens
-
5'-AMP
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q08499
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3',5'-cAMP + H2O
-
Homo sapiens 5'-AMP
-
?

Synonyms

Synonyms Comment Organism
PDE4 isoform Homo sapiens