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Literature summary for 3.1.4.53 extracted from
- Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor (2008), Mol. Pharmacol., 74, 1453-1462.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| isoproterenol | PDE4 activity is stimulated with 0.01 mM isoproterenol | Mus musculus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| rolipram | - |
Mus musculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cardiac myocyte | - |
Mus musculus | - |
| heart | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3',5'-cAMP + H2O | - |
Mus musculus | 5'-AMP | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PDE4 | - |
Mus musculus |
| phosphodiesterase 4 | - |
Mus musculus |
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Release 2023.1 (January 2023)
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