Protein Variants | Comment | Organism |
---|---|---|
additional information | mutation of Arr leads to suppression of induction of biofilm formation | Pseudomonas aeruginosa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
GTP | inhibition of the phosphodiesterase, reduction of tobramycin biofilm stimulation, and suppression of biofilm response, overview | Pseudomonas aeruginosa | |
additional information | inhibition of the enzyme leads to suppression of induction of biofilm formation | Pseudomonas aeruginosa | |
Nalidixic acid | reduction of tobramycin biofilm stimulation and suppression of biofilm response, overview | Pseudomonas aeruginosa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cyclic di-3',5'-guanylate + H2O | Pseudomonas aeruginosa | degradation | 5'-phosphoguanylyl(3'-5')guanosine | - |
? | |
additional information | Pseudomonas aeruginosa | Arr is required for induction of biofilms under DNA replication stress by a mechanism of stimulated adhesion of planktonic filaments having impaired DNA replication, the induction is suppressed by either inhibition or mutation of the c-di-GMP phosphodiesterase, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | - |
gene arr | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cyclic di-3',5'-guanylate + H2O | - |
Pseudomonas aeruginosa | 5'-phosphoguanylyl(3'-5')guanosine | - |
? | |
cyclic di-3',5'-guanylate + H2O | degradation | Pseudomonas aeruginosa | 5'-phosphoguanylyl(3'-5')guanosine | - |
? | |
additional information | Arr is required for induction of biofilms under DNA replication stress by a mechanism of stimulated adhesion of planktonic filaments having impaired DNA replication, the induction is suppressed by either inhibition or mutation of the c-di-GMP phosphodiesterase, overview | Pseudomonas aeruginosa | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Arr | - |
Pseudomonas aeruginosa |
c-di-GMP phosphodiesterase | - |
Pseudomonas aeruginosa |