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Literature summary for 3.1.4.52 extracted from
- Regulation of Vibrio polysaccharide synthesis and virulence factor production by CdgC, a GGDEF-EAL domain protein, in Vibrio cholerae (2007), J. Bacteriol., 189, 717-729.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Vibrio cholerae serotype O1 | CdgC regulates expression of genes required for Vibrio cholerae polysaccharide synthesis and the transcriptional regulator genes vpsR, vpsT, and hapR. CdgC also regulates expression of genes involved in extracellular protein secretion, flagellar biosynthesis, and virulence factor production. The regulons of CdgC and MbaA overlap, but with different timing | ? | - |
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Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Vibrio cholerae serotype O1 | - |
expression of genes cdgC and mbaA harboring both EAL and GGDEF motifs is higher in the rugose phase variant than in the smooth variant. CdgC regulates expression of genes required for Vibrio cholerae polysaccharide synthesis and the transcriptional regulator genes vpsR, vpsT, and hapR. CdgC also regulates expression of genes involved in extracellular protein secretion, flagellar biosynthesis, and virulence factor production. The regulons of CdgC and MbaA overlap, but with different timing | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | CdgC regulates expression of genes required for Vibrio cholerae polysaccharide synthesis and the transcriptional regulator genes vpsR, vpsT, and hapR. CdgC also regulates expression of genes involved in extracellular protein secretion, flagellar biosynthesis, and virulence factor production. The regulons of CdgC and MbaA overlap, but with different timing | Vibrio cholerae serotype O1 | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CdgC | - |
Vibrio cholerae serotype O1 |
| MbaA | - |
Vibrio cholerae serotype O1 |
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